BackgroundActs upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
DescriptionRHOU Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4
SpecificityHuman
IsotypeIgG
Uniprot IDQ7L0Q8
PurificationProtein G purified
ImmunogenRecombinant Human Rho-related GTP-binding protein RhoU protein (1-48AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRho-related GTP-binding protein RhoU, CDC42-like GTPase 1, GTP-binding protein-like 1, Rho GTPase-like protein ARHU, Ryu GTPase, Wnt-1 responsive Cdc42 homolog 1, WRCH-1, RHOU
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200