BackgroundTranscription factor that acts as a key regulator of spermatogenesis. Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters. Probably activates transcription of the testis-specific histone gene HIST1H1T.
DescriptionRFX2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP48378
Purification>95%, Protein G purified
ImmunogenRecombinant Human DNA-binding protein RFX2 protein (1-130AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesDNA-binding protein RFX2, Regulatory factor X 2, RFX2
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500