BackgroundRab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
DescriptionRABGEF1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9UJ41
Purification>95%, Protein G purified
ImmunogenRecombinant Human Rab5 GDP/GTP exchange factor protein (1-491AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRAP1, Rabaptin-5-associated exchange factor for Rab5, Rabex-5, RABGEF1, RABEX5
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200