BackgroundReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
DescriptionPTGER2 Recombinant Monoclonal Antibody [8D8]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP43116
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human PTGER2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesProstaglandin E2 receptor EP2 subtype (PGE receptor EP2 subtype) (PGE2 receptor EP2 subtype) (Prostanoid EP2 receptor), PTGER2
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200