BackgroundGrowth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
DescriptionPGF Recombinant Monoclonal Antibody [1B6]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP49763
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human PLGF
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesPlacenta growth factor (PlGF), PGF, PGFL PLGF
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200