BackgroundProgrammed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
DescriptionPD-1 Recombinant Monoclonal Antibody [9A9]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypehIgG4
Uniprot IDQ15116
PurificationAffinity Chromatography
ImmunogenRecombinant Human PD-1 protein
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCD279 antibody; CD279 antigen antibody; hPD 1 antibody; hPD l antibody; hPD-1 antibody; hSLE1 antibody; PD 1 antibody; PD-1 antibody; PD1 antibody; PDCD 1 antibody; PDCD1 antibody; PDCD1_HUMAN antibody; Programmed cell death 1 antibody; Programmed cell death 1 protein antibody; Programmed cell death protein 1 antibody; Protein PD 1 antibody; Protein PD-1 antibody; SLEB2 antibody; Systemic lupus erythematosus susceptibility 2 antibody
ApplicationELISA