BackgroundNeural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
DescriptionL1CAM Recombinant Monoclonal Antibody [14H7]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP32004
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human L1CAM
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesNeural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171), L1CAM, CAML1 MIC5
ApplicationELISA, IHC, FC; Recommended dilution: IHC:1:50-1:200, FC:1:50-1:200
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