BackgroundCatalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond By similarity. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).
DescriptionKYAT3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ6YP21
Purification>95%, Protein G purified
ImmunogenRecombinant Human Kynurenine--oxoglutarate transaminase 3 protein (1-454AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCysteine-S-conjugate beta-lyase 2, Kynurenine aminotransferase III, KATIII, Kynurenine--glyoxylate transaminase, Kynurenine--oxoglutarate transaminase III, KAT3, CCBL2
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200