BackgroundCytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
DescriptionIL1F10 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ8WWZ1
Purification>95%, Protein G purified
ImmunogenRecombinant Human Interleukin-1 family member 10 protein (1-152AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesIL-1F10, Family of interleukin 1-theta, FIL1 theta, IL-1HY2, IL-1 theta, IL-38, Interleukin-38, Interleukin-1 theta, Interleukin-1 HY2
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200