HP1-beta Polyclonal Antibody

Background
HP1beta is an isoform of the heterochromatin protein 1 (HP1) which plays a role in chromatin remodeling and transcriptional silencing. The HP1 chromo domain selectively recognizes methylated H3-K9, where this methylation is carried out by histone methyltransferase SUV39H1. SUV39H1-HP1 methylation is important for the correct localization of HP1 at heterochromatin and for transcriptional silencing.

Description
HP1-beta Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Specificity
Mouse, Human

Isotype
IgG

Uniprot ID
P83916

Purification
Affinity Purified

Immunogen
Synthetic peptide of human CBX1

Storage
Shipped at 4°C (Blue Ice). Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
CBX1; HP1B; chromobox homolog 1

Application
ELISA, IHC; Recommended dilution: ELISA:1:1000-1:2000, IHC:1:15-1:50