HP1 beta is an isoform of the heterochromatin protein 1 (HP1) which plays a role in chromatin remodeling and transcriptional silencing. The HP1 chromo domain selectively recognizes methylated H3-K9, where this methylation is carried out by histone methyltransferase SUV39H1. SUV39H1-HP1 methylation is important for the correct localization of HP1 at heterochromatin and for transcriptional silencing.
HP1-beta Polyclonal Antibody Unconjugated. Raised in: Rabbit.
Liquid. pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Synthetic peptide of human CBX1
Store at -20°C or -80°C. Avoid repeated freeze.
CBX1; HP1B; chromobox homolog 1
ELISA, IHC; Recommended dilution: ELISA:1:1000-1:2000, IHC:1:15-1:50