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HMGN3 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human prostate cancer using HMGN3 Polyclonal Antibody at dilution 1:100
Application: ELISA, IHC
Areas of Research: Chromatin Remodeling
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A59394-02020 µg $59.00 
A59394-05050 µg $256.00 
A59394-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.

Description
HMGN3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q15651

Purification
>95%, Protein G purified

Immunogen
Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
High mobility group nucleosome-binding domain-containing protein 3, HMGN3, TRIP7, PNAS-24, Thyroid receptor-interacting protein 7, TR-interacting protein 7, TRIP-7

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

User Guide & MSDS

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