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HDAC8 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human placenta tissue using HDAC8 Polyclonal Antibody at dilution 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using HDAC8 Polyclonal Antibody at dilution 1:100
Immunofluorescent analysis of Hela cells using HDAC8 Polyclonal Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L)
Application: ELISA, IF, IHC
Areas of Research: Histone Acetylation & Deacetylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A55962-02020 µg $59.00 
A55962-05050 µg $256.00 
A55962-100100 µg $359.00 
Availability: Usually Ships Within 1 Week 
Product Overview

Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Description
HDAC8 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9BY41

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Histone deacetylase 8 protein (1-377AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
HDAC8, HDACL1, CDA07

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

User Guide & MSDS

[User Guide]*
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