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HACE1 Polyclonal Antibody, HRP Conjugated

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Application: ELISA
Areas of Research: Cell Cycle
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A69056-05050 µg $249.00 
A69056-100100 µg $399.00 
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Product Overview

Background
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

Description
HACE1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q8IYU2

Purification
>95%, Protein G purified

Immunogen
Recombinant Human E3 ubiquitin-protein ligase HACE1 protein (333-442AA)

Storage
Shipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1, HACE1, KIAA1320

Application
ELISA

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