BackgroundEndogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. Permits diffusion of specific solutes through the outer membrane.
DescriptionGUCA2B Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
SpecificityHuman
IsotypeIgG
Uniprot IDQ16661
PurificationProtein G purified
ImmunogenRecombinant Human Guanylate cyclase activator 2B protein (37-112AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesGuanylate cyclase C-activating peptide II, GUCA2B
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200