BackgroundFunctions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
DescriptionFARP2 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO94887
PurificationProtein G purified
ImmunogenRecombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 protein (261-550AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesFERM, RhoGEF and pleckstrin domain-containing protein 2, FARP2, KIAA0793, PLEKHC3, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500