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DOK1 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human skin tissue using DOK1 Polyclonal Antibody at dilution 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using DOK1 Polyclonal Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using DOK1 Polyclonal Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L)
Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A55198-02020 µg $99.00 
A55198-05050 µg $256.00 
A55198-100100 µg $359.00 
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Product Overview

Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Description
DOK1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q99704

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Docking protein 1 protein (1-481AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Downstream of tyrosine kinase 1, p62(dok), pp62, DOK1

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

User Guide & MSDS

[User Guide]*
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