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DNMT3A Polyclonal Antibody, Biotin Conjugated

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Application: ELISA
Areas of Research: DNA Methylation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A52572-05050 µg $256.00 
A52572-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity

Description
DNMT3A Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9Y6K1

Purification
>95%, Protein G purified

Immunogen
Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
DNA methyltransferase HsaIIIA, DNMT3A

Application
ELISA

User Guide & MSDS

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