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Introduction to Epigenetics

DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).
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GADD45B Polyclonal Antibody, FITC Conjugated
GADD45B Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62628-05050 µg $256.00 Add to Cart
A62628-100100 µg $359.00 Add to Cart
Antibodies
GADD45B Polyclonal Antibody, HRP Conjugated
GADD45B Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62627-05050 µg $256.00 Add to Cart
A62627-100100 µg $359.00 Add to Cart
Antibodies
GADD45G Polyclonal Antibody
GADD45G Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57309-02020 µg $59.00 Add to Cart
A57309-05050 µg $256.00 Add to Cart
A57309-100100 µg $359.00 Add to Cart
Antibodies
GADD45G Polyclonal Antibody, Biotin Conjugated
GADD45G Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57312-05050 µg $256.00 Add to Cart
A57312-100100 µg $359.00 Add to Cart
Antibodies
GADD45G Polyclonal Antibody, FITC Conjugated
GADD45G Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57311-05050 µg $256.00 Add to Cart
A57311-100100 µg $359.00 Add to Cart
Antibodies
GADD45G Polyclonal Antibody, HRP Conjugated
GADD45G Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57310-05050 µg $256.00 Add to Cart
A57310-100100 µg $359.00 Add to Cart
Antibodies
HUS1 Polyclonal Antibody
HUS1 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54483-02020 µg $59.00 Add to Cart
A54483-05050 µg $256.00 Add to Cart
A54483-100100 µg $359.00 Add to Cart
Antibodies
HUS1 Polyclonal Antibody, Biotin Conjugated
HUS1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54480-05050 µg $256.00 Add to Cart
A54480-100100 µg $359.00 Add to Cart
Antibodies
HUS1 Polyclonal Antibody, FITC Conjugated
HUS1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54481-05050 µg $256.00 Add to Cart
A54481-100100 µg $359.00 Add to Cart
Antibodies
HUS1 Polyclonal Antibody, HRP Conjugated
HUS1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54482-05050 µg $256.00 Add to Cart
A54482-100100 µg $359.00 Add to Cart
Antibodies
KP6 Killer Toxin Polyclonal Antibody
KP6 Killer Toxin Polyclonal Antibody

Application: ELISA
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Ustilago maydis P6 virus
Trial Size Available: Yes
A64302-02020 µg $59.00 Add to Cart
A64302-05050 µg $256.00 Add to Cart
A64302-100100 µg $359.00 Add to Cart
Antibodies
KP6 Killer Toxin Polyclonal Antibody, Biotin Conjugated
KP6 Killer Toxin Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Ustilago maydis P6 virus
A64305-05050 µg $256.00 Add to Cart
A64305-100100 µg $359.00 Add to Cart
Antibodies
KP6 Killer Toxin Polyclonal Antibody, FITC Conjugated
KP6 Killer Toxin Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Ustilago maydis P6 virus
A64304-05050 µg $256.00 Add to Cart
A64304-100100 µg $359.00 Add to Cart
Antibodies
KP6 Killer Toxin Polyclonal Antibody, HRP Conjugated
KP6 Killer Toxin Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Ustilago maydis P6 virus
A64303-05050 µg $256.00 Add to Cart
A64303-100100 µg $359.00 Add to Cart
Antibodies
MGMT Polyclonal Antibody
MGMT Polyclonal Antibody

Citations (2)
Application: IF, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
A-1010-05050 µl $199.00 Add to Cart
A-1010-100100 µl $391.00 Add to Cart
Antibodies
MGMT Polyclonal Antibody
MGMT Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52416-02020 µg $59.00 Add to Cart
A52416-05050 µg $256.00 Add to Cart
A52416-100100 µg $359.00 Add to Cart
Antibodies
MGMT Polyclonal Antibody, Biotin Conjugated
MGMT Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52413-05050 µg $256.00 Add to Cart
A52413-100100 µg $359.00 Add to Cart
Antibodies
MGMT Polyclonal Antibody, FITC Conjugated
MGMT Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52414-05050 µg $256.00 Add to Cart
A52414-100100 µg $359.00 Add to Cart
Antibodies
MGMT Polyclonal Antibody, HRP Conjugated
MGMT Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52415-05050 µg $256.00 Add to Cart
A52415-100100 µg $359.00 Add to Cart
Antibodies
MND1 Polyclonal Antibody
MND1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A67662-02020 µg $59.00 Add to Cart
A67662-05050 µg $256.00 Add to Cart
A67662-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 41 to 60 (of 169 products)
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