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DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 21 to 40 (of 169 products)
ERCC6L2 Polyclonal Antibody, FITC Conjugated
ERCC6L2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62192-05050 µg $256.00 Add to Cart
A62192-100100 µg $359.00 Add to Cart
Antibodies
ERCC6L2 Polyclonal Antibody, HRP Conjugated
ERCC6L2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62191-05050 µg $256.00 Add to Cart
A62191-100100 µg $359.00 Add to Cart
Antibodies
FANCC Polyclonal Antibody
FANCC Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A62566-02020 µg $59.00 Add to Cart
A62566-05050 µg $256.00 Add to Cart
A62566-100100 µg $359.00 Add to Cart
Antibodies
FANCC Polyclonal Antibody, Biotin Conjugated
FANCC Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62569-05050 µg $256.00 Add to Cart
A62569-100100 µg $359.00 Add to Cart
Antibodies
FANCC Polyclonal Antibody, FITC Conjugated
FANCC Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62568-05050 µg $256.00 Add to Cart
A62568-100100 µg $359.00 Add to Cart
Antibodies
FANCC Polyclonal Antibody, HRP Conjugated
FANCC Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62567-05050 µg $256.00 Add to Cart
A62567-100100 µg $359.00 Add to Cart
Antibodies
FANCD2 Polyclonal Antibody
FANCD2 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A67350-02020 µg $59.00 Add to Cart
A67350-05050 µg $256.00 Add to Cart
A67350-100100 µg $359.00 Add to Cart
Antibodies
FANCD2 Polyclonal Antibody, Biotin Conjugated
FANCD2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67353-05050 µg $256.00 Add to Cart
A67353-100100 µg $359.00 Add to Cart
Antibodies
FANCD2 Polyclonal Antibody, FITC Conjugated
FANCD2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67352-05050 µg $256.00 Add to Cart
A67352-100100 µg $359.00 Add to Cart
Antibodies
FANCD2 Polyclonal Antibody, HRP Conjugated
FANCD2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67351-05050 µg $256.00 Add to Cart
A67351-100100 µg $359.00 Add to Cart
Antibodies
FANCL Polyclonal Antibody
FANCL Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69263-02020 µg $59.00 Add to Cart
A69263-05050 µg $249.00 Add to Cart
A69263-100100 µg $399.00 Add to Cart
Antibodies
FANCL Polyclonal Antibody, Biotin Conjugated
FANCL Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69266-05050 µg $249.00 Add to Cart
A69266-100100 µg $399.00 Add to Cart
Antibodies
FANCL Polyclonal Antibody, FITC Conjugated
FANCL Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69265-05050 µg $249.00 Add to Cart
A69265-100100 µg $399.00 Add to Cart
Antibodies
FANCL Polyclonal Antibody, HRP Conjugated
FANCL Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69264-05050 µg $249.00 Add to Cart
A69264-100100 µg $399.00 Add to Cart
Antibodies
GADD45A Polyclonal Antibody
GADD45A Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A56859-02020 µg $59.00 Add to Cart
A56859-05050 µg $256.00 Add to Cart
A56859-100100 µg $359.00 Add to Cart
Antibodies
GADD45A Polyclonal Antibody, Biotin Conjugated
GADD45A Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56862-05050 µg $256.00 Add to Cart
A56862-100100 µg $359.00 Add to Cart
Antibodies
GADD45A Polyclonal Antibody, FITC Conjugated
GADD45A Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56861-05050 µg $256.00 Add to Cart
A56861-100100 µg $359.00 Add to Cart
Antibodies
GADD45A Polyclonal Antibody, HRP Conjugated
GADD45A Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A56860-05050 µg $256.00 Add to Cart
A56860-100100 µg $359.00 Add to Cart
Antibodies
GADD45B Polyclonal Antibody
GADD45B Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A62626-02020 µg $59.00 Add to Cart
A62626-05050 µg $256.00 Add to Cart
A62626-100100 µg $359.00 Add to Cart
Antibodies
GADD45B Polyclonal Antibody, Biotin Conjugated
GADD45B Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62629-05050 µg $256.00 Add to Cart
A62629-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 21 to 40 (of 169 products)
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