FANCL Polyclonal Antibody, FITC Conjugated

Background
Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.

Description
FANCL Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9NW38

Purification
>95%, Protein G purified

Immunogen
Recombinant Human E3 ubiquitin-protein ligase FANCL protein (138-248AA)

Storage
Shipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
E3 ubiquitin-protein ligase FANCL, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, FAAP43, RING-type E3 ubiquitin transferase FANCL, FANCL, PHF9

Application
ELISA; Recommended dilution: ELISA 1:100-1:500