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DCP2 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human testis tissue using DCP2 Polyclonal Antibody at dilution 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using DCP2 Polyclonal Antibody at dilution 1:100
Application: ELISA, IHC
Areas of Research: RNA Processing and Modification
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A55910-02020 µg $59.00 
A55910-05050 µg $256.00 
A55910-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.

Description
DCP2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q8IU60

Purification
>95%, Protein G purified

Immunogen
Recombinant Human m7GpppN-mRNA hydrolase (1-385AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Nucleoside diphosphate-linked moiety X motif 20, mRNA-decapping enzyme 2, NUDT20, DCP2

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

User Guide & MSDS

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