BackgroundDIAPH1 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. In hearing it may play a role in the regulation of actin polymerization in hair cells.
DescriptionCYB5R3 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP00387
Purification>95%, Protein G purified
ImmunogenRecombinant Human NADH-cytochrome b5 reductase 3 protein (1-301AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500