BackgroundThis gene produces a cullin protein, essential for polyubiquitination and protein degradation. It forms a core E3 ubiquitin ligase complex and contributes to late endosome maturation. Mutations can lead to type 2E pseudohypoaldosteronism. Various isoforms result from alternative splicing.
DescriptionCUL3 Recombinant Monoclonal Antibody [7B6]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ13618
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Cullin 3
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCullin-3 (CUL-3), CUL3, KIAA0617
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200