BackgroundS-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.
DescriptionCMTR2 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ8IYT2
Purification>95%, Protein G purified
ImmunogenRecombinant Human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 protein (301-600AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC:2.1.1.296), CMTR2, AFT, FTSJD1, Cap methyltransferase 2, Cap2 2'O-ribose methyltransferase 2, HMTr2, MTr2, FtsJ methyltransferase domain-containing protein 1, Protein adrift homolog
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500
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