BackgroundHydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
DescriptionCbs Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDQ91WT9
PurificationProtein G purified
ImmunogenRecombinant Mouse Cystathionine beta-synthase protein (2-561AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCystathionine beta-synthase, Beta-thionase, Serine sulfhydrase, Cbs
ApplicationELISA, IF; Recommended dilution: IF:1:50-1:200