BackgroundSymmetrically cleaves beta-carotene into two molecules of retinal. The reaction proceeds in three stages, epoxidation of the 15,15'-double bond, hydration of the double bond leading to ring opening, and oxidative cleavage of the diol formed.
DescriptionBCO1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9HAY6
PurificationProtein G purified
ImmunogenRecombinant Human Beta,beta-carotene 15,15'-dioxygenase protein (1-300AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesBeta, beta-carotene 15, 15'-monooxygenase, Beta-carotene dioxygenase 1, Beta-carotene oxygenase 1, BCO1
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200