BackgroundCatalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
DescriptionAPOBEC1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP41238
Purification>95%, Protein G purified
ImmunogenRecombinant Human C->U-editing enzyme APOBEC-1 protein (1-172AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesC->U-editing enzyme APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, HEPR, mRNA(cytosine(6666)) deaminase 1, APOBEC1
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000
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