This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
ADA Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 1-363 of human ADA (NP_000013.2).
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
ADA; adenosine deaminase
WB, IF; Recommended dilution: WB 1:500 - 1:2000, IF 1:50 - 1:200