BackgroundTetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-/-Phe-77' bond of synaptobrevin-2.
DescriptiontetX Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityClostridium tetani
IsotypeIgG
Uniprot IDP04958
Purification>95%, Protein G purified
ImmunogenRecombinant Clostridium tetani Tetanus toxin protein (123-573AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesTentoxylysin, Tetanus toxin chain L, Tetanus toxin chain H, CTC_p60, tetX
ApplicationELISA