BackgroundInvolved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes.
DescriptionSLC7A7 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9UM01
Purification>95%, Protein G purified
ImmunogenRecombinant Human Y+L amino acid transporter 1 protein (325-382AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesY+L amino acid transporter 1, Monocyte amino acid permease 2, MOP-2, Solute carrier family 7 member 7, y(+)L-type amino acid transporter 1, Y+LAT1, y+LAT-1, SLC7A7
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000