BackgroundInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
DescriptionRGS2 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP41220
Purification>95%, Protein G purified
ImmunogenRecombinant Human Regulator of G-protein signaling 2 protein (1-211AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesRGS2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, GIG31, G0S8, RGS2
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000