BackgroundHousekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress (PubMed:25865492).
DescriptionPYCR2 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ96C36
PurificationAffinity purified
ImmunogenRecombinant Human Pyrroline-5-carboxylate reductase 2 protein (2-320AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesPyrroline-5-carboxylate reductase 2 (EC:1.5.1.2), P5C reductase 2, P5CR 2, PYCR2
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000