BackgroundThis gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
DescriptionPPAR gamma Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP37231
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 100-200 of human PPARγ (NP_056953.2).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesPPARG; CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma; peroxisome proliferator-activated receptor gamma
ApplicationIHC, IF; Recommended dilution: IHC 1:50 - 1:200, IF 1:50 - 1:200