BackgroundGrowth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
DescriptionOSM Recombinant Monoclonal Antibody [31E7]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypehIgG1
Uniprot IDP13725
PurificationAffinity Chromatography
ImmunogenRecombinant Human OSM protein
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesOncostatin-M (OSM), OSM
ApplicationELISA