BackgroundDNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
DescriptionOGG1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO15527
Purification>95%, Protein G purified
ImmunogenRecombinant Human N-glycosylase/DNA lyase protein (1-345AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesN-glycosylase/DNA lyaseIncluding the following 2 domains:8-oxoguanine DNA glycosylase (EC:3.2.2.-)DNA-(apurinic or apyrimidinic site) lyase (EC:4.2.99.18), AP lyase, OGG1, MMH, MUTM, OGH1
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000
