BackgroundCatalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Plays also a role in the regulation of the endocytic trafficking of EGFR (By similarity).
DescriptionNSDHL Recombinant Monoclonal Antibody [20F2]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ15738
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human NSDHL
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170) (Protein H105e3), NSDHL, H105E3
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:50-1:200
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