BackgroundPlays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization By similarity. Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Ref. 15 Medin is the main constituent of aortic medial amyloid.
DescriptionMFGE8 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ08431
Purification>95%, Protein G purified
ImmunogenRecombinant Human Lactadherin protein (25-334AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesBreast epithelial antigen BA46 HMFG MFGM Milk fat globule-EGF factor 8 Short name=MFG-E8 SED1 Cleaved into the following 2 chains: Lactadherin short form Medin
ApplicationELISA; Recommended dilution: ELISA 1:100-1:500