BackgroundComponent of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.
DescriptionMCM9 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9NXL9
Purification>95%, Protein G purified
ImmunogenRecombinant Human DNA helicase MCM9 protein (1-391AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesDNA helicase MCM9 (EC:3.6.4.12), hMCM9, MCM9, C6orf61, MCMDC1, Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000