BackgroundBifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
DescriptionLECT1 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO75829
Purification>95%, Protein G purified
ImmunogenRecombinant Human Leukocyte cell-derived chemotaxin 1 protein (215-334AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesLeukocyte cell-derived chemotaxin 1Cleaved into the following 2 chains:Chondrosurfactant protein, CH-SPChondromodulin-1, LECT1, CHMI, Chondromodulin-I, ChM-I
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000