BackgroundAssociates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.
DescriptionIFNAR2 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP48551
Purification>95%, Protein G purified
ImmunogenRecombinant Human Interferon alpha/beta receptor 2 protein (27-243AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesIFN-R-2, IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, Interferon alpha binding protein
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000