HP1α is an isoform of the heterochromatin protein 1 (HP1) which plays a role in chromatin remodeling and transcriptional silencing. The HP1 chromo domain selectively recognizes methylated H3-K9, where this methylation is carried out by histone methyltransferase SUV39H1. SUV39H1-HP1 methylation is important for the correct localization of HP1 at heterochromatin and for transcriptional silencing.
HP1-alpha Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Synthesized peptide derived from the Internal region of human HP1α.
Store at -20°C or -80°C. Avoid repeated freeze.
CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
WB, IHC, IF, ELISA; Recommended dilution: WB:1/500-1/2000, IHC:1/100-1/300, IF:1/200-1/1000, ELISA:1/20000