HLA-G Recombinant Monoclonal Antibody [17A5]

Background
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

Description
HLA-G Recombinant Monoclonal Antibody [17A5]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human

Isotype
Rabbit IgG

Uniprot ID
P17693

Purification
Affinity Chromatography

Immunogen
A synthesized peptide derived from Human HLA-G

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
HLA class I histocompatibility antigen, alpha chain G (HLA G antigen) (MHC class I antigen G), HLA-G, HLA-6.0 HLAG

Application
ELISA, FC; Recommended dilution: FC:1:50-1:200