BackgroundCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
DescriptionHistone H2BK Monoclonal Antibody, clone RMC411A. Unconjugated. Raised in: Rabbit.
ConcentrationInquire
FormulationLiquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
Isotype IgG
Uniprot IDO60814
PurificationAffinity Purified
ImmunogenA synthesized peptide
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesHistone H2B type 1-K, H2B K, HIRA-interacting protein 1, HIST1H2BK, H2BFT, HIRIP1
ApplicationELISA, WB, IHC; Recommended dilution: WB: 1:5000-1:10000, IHC: 1:50-1:500
VCU0006