BackgroundCalcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
DescriptionGSN Recombinant Monoclonal Antibody [16H9]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP06396
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human GSN
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin), GSN
ApplicationELISA, IF, FC; Recommended dilution: IF:1:50-1:200, FC:1:50-1:200