BackgroundComponent of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
DescriptionGRIN1 Recombinant Monoclonal Antibody [24F5]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ05586
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human GRIN1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGlutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1), GRIN1, NMDAR1
ApplicationELISA, FC; Recommended dilution: FC:1:50-1:200
Celebrate our 20th year anniversary with gifts on purchases above $300!
» Learn more
Cart (0)
