BackgroundInhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
DescriptionGMNN Recombinant Monoclonal Antibody [8H8]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDO75496
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Geminin
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGeminin, GMNN
ApplicationELISA, IF; Recommended dilution: IF:1:20-1:200