BackgroundThis gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
DescriptionGLP1R Recombinant Monoclonal Antibody [7H7]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypehIgG4
Uniprot IDP43220
PurificationAffinity Chromatography
ImmunogenRecombinant Human GLP1R protein
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesGLP 1 R antibody; GLP 1 receptor antibody; GLP 1R antibody; GLP antibody; GLP-1 receptor antibody; GLP-1-R antibody; GLP-1R antibody; GLP1R antibody; GLP1R_HUMAN antibody; Glucagon like peptide 1 receptor antibody; Glucagon-like peptide 1 receptor antibody; MGC138331 antibody; OTTHUMP00000016340 antibody
ApplicationELISA