BackgroundProbable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
DescriptionFBXW10 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ5XX13
Purification>95%, Protein G purified
ImmunogenRecombinant Human F-box/WD repeat-containing protein 10 protein (701-1000AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesF-box/WD repeat-containing protein 10, FBXW10, F-box and WD-40 domain-containing protein 10, Ubiquitin ligase-specificity factor
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000