BackgroundGuanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles.
DescriptionDENND1A Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ8TEH3
Purification>95%, Protein G purified
ImmunogenRecombinant Human DENN domain-containing protein 1A protein (1-559AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesDENN domain-containing protein 1A, DENND1A, FAM31A, KIAA1608, Connecdenn 1, Connecdenn, Protein FAM31A
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000