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DDX42 Polyclonal Antibody, Biotin Conjugated

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Application: ELISA
Areas of Research: RNA Processing and Modification
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A58751-05050 µg $256.00 
A58751-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Description
DDX42 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q86XP3

Purification
>95%, Protein G purified

Immunogen
Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
ATP-dependent RNA helicase DDX42 (EC:3.6.4.13), DDX42, DEAD box protein 42, RNA helicase-like protein, RHELP, RNA helicase-related protein, RNAHP, SF3b DEAD box protein, Splicing factor 3B-associated 125 kDa protein, SF3b125

Application
ELISA

User Guide & MSDS

[User Guide]*
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